Contribution of specific Nod1 and Nod2 stimulation to the adaptive immune response

特异性 Nod1 和 Nod2 刺激对适应性免疫反应的贡献

• 批准号: 180331
• 负责人: Gamelas Magalhaes Joao
• 金额: $ 3.28万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Fellowship Programs
• 财政年份: 2009
• 资助国家: 加拿大
• 起止时间: 2009-02-01 至 2010-02-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=180331&lang=en
• 关键词: Adaptive Immunity; Chimeric And Transgenic Mouse; Dendritic Cell; Elisa; Elispot; Facs; Immunoregulation; Innate Sensing; Ko; Nod Proteins; Western Blot

Nod1 and Nod2 are pattern recognition molecule (PRM) of the innate immune system belonging to the NOD-like receptor (NLR) family. These cytoplasmic PRMs are implicated in the recognition of bacterial pepdidoglycan (PGN), a major component of bacterial cel

Nod1和Nod2是先天免疫系统的模式识别分子（PRM），属于nod样受体（NLR）家族。这些细胞质PRMs与细菌肽聚糖（PGN）的识别有关，PGN是细菌细胞的主要成分