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Computation and theory to predict structures and mechanisms for protein misfolding in amyotrophic lateral sclerosis

Computation and theory to predict structures and mechanisms for protein misfolding in amyotrophic lateral sclerosis
预测肌萎缩侧索硬化症蛋白质错误折叠结构和机制的计算和理论
批准号：
321932
负责人：
Plotkin Steven S
金额：
$46.38万
依托单位：
University of British Columbia
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2015
资助国家：
加拿大
项目状态：
已结题
起止时间：
2015-03-01 至 2020-03-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=321932&lang=en
关键词：
Alzheimer'S Disease Amyotrophic Lateral Sclerosis Computational Modeling Molecular Dynamics Simulation Multiple Relevance Neurodegenerative Disease Prion Protein Aggregation Protein Folding Protein Misfolding

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中文摘要
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英文摘要
As we age, we begin to face an onslaught of threats to our health that evolution has not protected us against. Many of these include degenerative diseases such as Alzheimer's disease, Parkinson's disease, and Lou Gehrig's disease or ALS. It is up to us to
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