Pannexins in cytotoxic swelling-induced cell death

Pannexins 在细胞毒性肿胀诱导的细胞死亡中的作用

• 批准号: 322010
• 负责人: MacVicar Brian A
• 金额: $ 56.28万
• 依托单位: University of British Columbia
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2015
• 资助国家: 加拿大
• 起止时间: 2015-03-01 至 2020-03-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=322010&lang=en
• 关键词: Brain Swelling; Cytotoxic Neuronal Edema; Hippocampus; Neuron; Pannexin; Stroke; Two Photon Microscopy; Whole Cell Voltage Clamp

Swelling of the brain, termed brain edema, has terrible consequences for patients. Large strokes that affect substantial regions of the brain, head injury, hypoxia or infection can lead to brain edema. The swelling of the brain under these circumstances

大脑肿胀（称为脑水肿）会给患者带来可怕的后果。 影响大脑大部分区域的大中风、头部受伤、缺氧或感染都可能导致脑水肿。 在这种情况下大脑肿胀