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Using genetically engineered mouse models to define variables producing pancreatic ductal adenocarcinoma heterogeneity

Using genetically engineered mouse models to define variables producing pancreatic ductal adenocarcinoma heterogeneity
使用基因工程小鼠模型来定义产生胰腺导管腺癌异质性的变量
批准号：
323460
负责人：
Kopp Janel
金额：
$46.96万
依托单位：
University of British Columbia
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2015
资助国家：
加拿大
项目状态：
已结题
起止时间：
2015-03-01 至 2020-03-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=323460&lang=en
关键词：
Biomarkers Diagnostic Gene Signatures Mouse Genetic Models Pancreatic Cancer Pancreatic Ductal Adenocarcinoma Premalignant Lesions Tumor Heterogeneity Tumorigenesis

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英文摘要
Tumor heterogeneity is largely thought to arise from different gene mutation events. Mounting evidence also suggests that distinct tumor-initiating cell types, or cells of origin, may also contribute to heterogeneity in prostate and breast cancer. However
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Role of inflammation during the genesis of intraductal papillary mucinous neoplasia associated pancreatic ductal adenocarcinoma
  • 批准号：
    390103
  • 项目类别：
    Operating Grants
  • 资助金额：
    $79.42万
  • 财政年份：
    2018
  • 负责人：
    Kopp Janel
  • 依托单位：
    University of British Columbia
Molecular And Cellular Mechanisms Leading To Pancreatic Cancer Heterogeneity
  • 批准号：
    340711
  • 项目类别：
    Salary Programs
  • 资助金额：
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  • 财政年份：
    2015
  • 负责人：
    Kopp Janel
  • 依托单位：
    University of British Columbia