Mechanisms regulating RET receptor-mediated tumourigenesis

RET 受体介导的肿瘤发生的调节机制

• 批准号: 322239
• 负责人: Mulligan Lois M
• 金额: $ 50.67万
• 依托单位: Queen's University (Kingston, Ontario)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2015
• 资助国家: 加拿大
• 起止时间: 2015-03-01 至 2020-03-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=322239&lang=en
• 关键词: Colon Cancer; Multicancer Relevance; Pancreatic Carcinoma; Prostate Carcinoma; Receptor Tyrosine Kinase; Ret; Tumour Invasion

Under normal conditions, cells require signals from their surroundings in order to grow, to move, or just to survive. These processes are essential for normal development, but they can be hijacked in cancer cells, allowing the disease to grow and spread.

在正常情况下，细胞需要来自周围环境的信号才能生长、移动或只是为了生存。这些过程对正常发育是必不可少的，但它们可能被劫持在癌细胞中，使疾病得以生长和传播。