Identifying projection-specific changes in reward circuit activity that underlie behavioral changes and reward-seeking driven by cocaine

识别奖励回路活动中特定于预测的变化，这些变化是可卡因驱动的行为变化和奖励寻求的基础

• 批准号: 338605
• 负责人: Mills Fergil P
• 金额: $ 10.93万
• 依托单位: Massachusetts Institute of Technology
• 依托单位国家: 加拿大
• 项目类别: Fellowship Programs
• 财政年份: 2015
• 资助国家: 加拿大
• 起止时间: 2015-11-01 至 2018-11-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=338605&lang=en
• 关键词: Addiction; Behavioural Conditioning; Cocaine; Dopamine; Drug-Seeking Behaviours; Fiber Photometry; Neural Circuitry Of The Brain; Optogenetic Stimulation

Drug addiction is a serious health issue in Canada and throughout the world. A major goal of addiction research has been to identify the circuit-level changes in activity caused by drugs of abuse that 'hijack' the normal processes underlying reward learni

吸毒成瘾在加拿大和全世界都是一个严重的健康问题。成瘾研究的一个主要目标是确定滥用药物导致的活动回路水平的变化，药物滥用‘劫持’了潜在的奖励学习的正常过程