Kinetochore-microtubule attachments and age-related aneuploidy in mammalian oocytes.

哺乳动物卵母细胞着丝粒微管附着和年龄相关的非整倍性。

• 批准号: 339113
• 负责人: Haverfield Jenna
• 金额: $ 6.56万
• 依托单位: Centre hospitalier de l'Universit de Montral (CHUM)
• 依托单位国家: 加拿大
• 项目类别: Fellowship Programs
• 财政年份: 2015
• 资助国家: 加拿大
• 起止时间: 2015-11-01 至 2017-11-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=339113&lang=en
• 关键词: Aging; Aneuploidy; Female Infertility; Live Cell Imaging; Microinjection; Oocytes

One of the major causes of pregnancy loss and birth defects such as Down Syndrome is a defect with the woman's egg, whereby the egg has too few or too many chromosomes. The chance of a woman's egg having the wrong number of chromosomes increases as she ge

流产和出生缺陷（如唐氏综合症）的主要原因之一是女性卵子的缺陷，即卵子染色体过少或过多。随着年龄的增长，女性卵子中染色体数量错误的几率也会增加