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Systems Biology Approaches to Decipher Novel Mechanisms and Markers of Antibody Mediated Rejection in Kidney Transplantation

Systems Biology Approaches to Decipher Novel Mechanisms and Markers of Antibody Mediated Rejection in Kidney Transplantation
系统生物学方法破译肾移植中抗体介导的排斥反应的新机制和标志物
批准号：
350627
负责人：
Konvalinka Ana
金额：
$6.65万
依托单位：
University Health Network (Toronto)
依托单位国家：
加拿大
项目类别：
Salary Programs
财政年份：
2016
资助国家：
加拿大
项目状态：
已结题
起止时间：
2016-02-01 至 2019-02-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=350627&lang=en
关键词：
Anti-Hla Antibodies Antibody Mediated Rejection Kidney Biopsy Kidney Transplantation Non-Hla Antibodies Protein Microarrays Proteomics System Biology

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中文摘要
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英文摘要
Kidney transplantation is the ideal treatment for patients whose kidneys fail. However, in addition to organ shortage, 30% of kidney grafts are lost prematurely, mainly due to antibody-mediated rejection (AMR), which lacks effective treatment. AMR is the
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