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Evaluation of the anti-angiogenic and neuroprotective effects of the BMP antagonist COCO for the treatment of neovascular ocular pathologies.

Evaluation of the anti-angiogenic and neuroprotective effects of the BMP antagonist COCO for the treatment of neovascular ocular pathologies.
评估 BMP 拮抗剂 COCO 治疗新生血管眼部病变的抗血管生成和神经保护作用。
批准号:
343413
负责人:
Larrivee Bruno
金额:
$41.77万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2016
资助国家:
加拿大
项目状态:
已结题
起止时间:
2016-03-01 至 2021-03-01

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英文摘要
Multiple diseases of the eye, such as age-related macular degeneration (AMD) and retinopathy of prematurity (ROP), are characterized by the excessive growth of abnormal blood vessels. Current treatments for these conditions include agents targeting the gr
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Role of COCO/Dand5 in visual function and assessment of its therapeutic potential for ocular pathologies.
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