HoliCOW - A holobiont strategy to uncover the core microbiome in cows

HoliCOW - 揭示奶牛核心微生物群的全息生物策略

• 批准号: FT230100560
• 负责人: Prof Phillip Pope
• 金额: $ 76.68万
• 依托单位: Queensland University of Technology
• 依托单位国家: 澳大利亚
• 项目类别: ARC Future Fellowships
• 财政年份: 2024
• 资助国家: 澳大利亚
• 起止时间: 2024-02-01 至 2028-01-31
• 项目状态: 未结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/FT230100560
• 关键词: HoliCOW; holobiont; strategy; uncover; core

Human population growth is driving a rise in cattle production for food, which necessitates sustainable practices that simultaneously optimise animal nutrition while reducing methane emissions, a critical greenhouse gas. This project aims to unravel and exploit biological connections across the cow holobiont, which pertains to the feed cows eat, their bodily function and the microbes in their rumen. This project will leverage multi-layered molecular data derived from the cow holobiont to identify, characterise and ultimately control the core rumen microbiome that causes methane production in animals. The outcome will be new knowledge to facilitate microbiome-based interventions that benefit animal production and reduce its carbon footprint.

人口增长正在推动食用牛产量的增加，这需要可持续的做法，同时优化动物营养，同时减少甲烷排放，这是一种关键的温室气体。该项目旨在解开和利用奶牛全生物体之间的生物联系，这与奶牛吃的饲料，它们的身体功能和瘤胃中的微生物有关。该项目将利用来自奶牛全生物群的多层分子数据来识别，识别并最终控制导致动物甲烷产生的核心瘤胃微生物组。其成果将是促进基于微生物组的干预措施的新知识，这些干预措施有利于动物生产并减少其碳足迹。