PGX technology for drying of biopolymers and their impregnation with bioactives

用于生物聚合物干燥及其生物活性物质浸渍的 PGX 技术

• 批准号: 500236-2016
• 负责人: Temelli, Feral
• 金额: $ 7.83万
• 依托单位: University of Alberta
• 依托单位国家: 加拿大
• 项目类别: Collaborative Research and Development Grants
• 财政年份: 2016
• 资助国家: 加拿大
• 起止时间: 2016-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=607988
• 关键词: PGX; technology; drying; biopolymers; their

PGX (Pressurized Gas eXpanded liquid) technology has been developed and patented by the applicants at the University of Alberta. It is licensed to Ceapro Inc for them to scale it up from the laboratory to commercial scale. With this technology it is possible to dry high molecular weight biopolymers, like polysaccharides or proteins, and generate powders with different characteristics. It is challenging to perform such drying using traditional technologies because high molecular weight biopolymers form highly viscous or very thick solutions. By controlling the processing parameters associated with the PGX technology, powders in different forms, ranging from very fine to coarse can be obtained. Because the powders obtained have a large surface area, they can be used as a carrier for other "natural" components with health benefits. Such bioactive components can be deposited onto the powders in a second step of the PGX process. Because the bioactive components are in general sensitive to heat and can be damaged easily, the low processing temperature of 40oC is particularly suitable for their handling. It is anticipated that such carrier systems for bioactive ingredients would make them more effective in the human body. The proposed research aims to study the formation of such ingredients based on different bioactive/biopolymer combinations and to carry out detailed characterization to better understand their interactions and performance of the technology for a variety of ingredients. The findings will be invaluable to expand the utilization of the technology and to generate novel high-value ingredients, targeting applications in functional food, dietary supplement and cosmetic products with far reaching benefits. Training of highly qualified personnel by the research team members working in close collaboration will contribute to meeting the demand for such individuals. The proposed research is essential to achieve the full potential of this promising technology at commercial scale and contribute to growing the bioeconomy.

PGX（加压气体膨胀液体）技术已经由申请人在阿尔伯塔大学开发并获得专利。它被授权给Ceapro Inc，以便他们将其从实验室规模扩大到商业规模。利用该技术，可以干燥高分子量生物聚合物，如多糖或蛋白质，并生成具有不同特性的粉末。使用传统技术进行这种干燥是具有挑战性的，因为高分子量生物聚合物形成高粘度或非常稠的溶液。通过控制与PGX技术相关的工艺参数，可以获得从极细到粗的不同形式的粉末。由于获得的粉末具有大的表面积，它们可以用作其他具有健康益处的“天然”成分的载体。这样的生物活性组分可以在PGX方法的第二步中沉积到粉末上。由于生物活性成分通常对热敏感，并且容易损坏，因此40 ℃的低加工温度特别适合其处理。预期这种用于生物活性成分的载体系统将使它们在人体中更有效。拟议的研究旨在研究基于不同生物活性/生物聚合物组合的这些成分的形成，并进行详细的表征，以更好地了解它们的相互作用和各种成分的技术性能。这些发现对于扩大该技术的利用和产生新的高价值成分具有非常宝贵的价值，目标是在功能性食品，膳食补充剂和化妆品中应用，具有深远的利益。研究小组成员密切合作，培训高素质的人员，将有助于满足对这些人员的需求。拟议的研究对于在商业规模上充分发挥这一有前途的技术的潜力并促进生物经济的发展至关重要。