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High-throughput behavioural neurogenetic characterization and precise structure-function analysis of genes and gene variants associated with Autism Spectrum Disorder using Caenorhabditis elegans.

High-throughput behavioural neurogenetic characterization and precise structure-function analysis of genes and gene variants associated with Autism Spectrum Disorder using Caenorhabditis elegans.
使用秀丽隐杆线虫对与自闭症谱系障碍相关的基因和基因变异进行高通量行为神经遗传学表征和精确结构功能分析。
批准号：
367818
负责人：
McDiarmid Troy A
金额：
$7.65万
依托单位：
University of British Columbia
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2016
资助国家：
加拿大
项目状态：
已结题
起止时间：
2016-10-01 至 2019-10-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=367818&lang=en
关键词：
Autism Spectrum Disorder Genetics Behaviour Genetics Behavioural Neuroscience Caenorhabditis Elegans Crispr-Cas9 Genetic Model Organisms Genome Engineering Habituation High-Throughput Behavioural Phenotyping Molecular Genetic Structure-Function A

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英文摘要
A primary challenge in investigations of genes associated with Autism Spectrum Disorder (ASD) is the lack of a model system in which to characterize the large number of candidate risk genes in a rapid, cost-effective manner. The time and money constraints
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