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Interrogation of drug and toxin mechanism of action by a matrix of chemogenomic profiles in human cells

Interrogation of drug and toxin mechanism of action by a matrix of chemogenomic profiles in human cells
通过人体细胞化学基因组谱矩阵询问药物和毒素的作用机制
批准号:
356374
负责人:
Tyers Michael D
金额:
$60.19万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2016
资助国家:
加拿大
项目状态:
已结题
起止时间:
2016-10-01 至 2020-10-01

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中文摘要
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英文摘要
This project aims to exploit a new technology that will enable drug and toxin mechanism of action to be determined directly and systematically in human cells. This approach, called chemogenomic profiling, is based on a revolutionary new method called CRIS
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Architecture and chemical modulation of genetic networks
  • 批准号:
    390551
  • 项目类别:
    Operating Grants
  • 资助金额:
    $339.78万
  • 财政年份:
    2018
  • 负责人:
    Tyers Michael D
  • 依托单位:
Canada Research Chair - Tier 1 - CIHR Funded
  • 批准号:
    384882
  • 项目类别:
  • 资助金额:
    $101.99万
  • 财政年份:
    2017
  • 负责人:
    Tyers Michael D
  • 依托单位:
A synthetic biology platform to generate and screen natural product-like chemical space for novel antibiotic activities
  • 批准号:
    372146
  • 项目类别:
    Operating Grants
  • 资助金额:
    $82.76万
  • 财政年份:
    2017
  • 负责人:
    Tyers Michael D
  • 依托单位:
Systems biology of cell size homeostasis
  • 批准号:
    346481
  • 项目类别:
    Operating Grants
  • 资助金额:
    $41.77万
  • 财政年份:
    2016
  • 负责人:
    Tyers Michael D
  • 依托单位:
海外基金