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The great escape: Improving the activity of chemotherapeutics delivered by antibody-drug conjugates with integrated endosome escape and nuclear-directional trafficking control capabilies

The great escape: Improving the activity of chemotherapeutics delivered by antibody-drug conjugates with integrated endosome escape and nuclear-directional trafficking control capabilies
伟大的逃亡：通过具有整合的内体逃逸和核定向运输控制能力的抗体-药物偶联物来提高化疗药物的活性
批准号：
358262
负责人：
Leyton Jeffrey V
金额：
$41.16万
依托单位：
Universit de Sherbrooke
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2016
资助国家：
加拿大
项目状态：
已结题
起止时间：
2016-10-01 至 2021-10-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=358262&lang=en
关键词：
Antibody-Drug Conjugates Drug Intracellular Accumulation Nuclear Routing And Accumulation Pet Imaging In Drug Development Selective Endosome Escape Targeted Chemotherapy

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The image of the 'therapeutic missile' commonly used to present targeted drug delivery agents emphasizes precision, control, and efficiency. For the next evolution of cancer treatment, antibody-drug conjugates (ADCs) are a great representative of this con
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    445112
  • 项目类别：
    Operating Grants
  • 资助金额：
    $42.35万
  • 财政年份：
    2021
  • 负责人：
    Leyton Jeffrey V
  • 依托单位：
    Universit de Sherbrooke