Bioaerosols and airborne spread of diseases in animal production operations
动物生产作业中的生物气溶胶和疾病的空气传播
基本信息
- 批准号:RGPIN-2015-05965
- 负责人:
- 金额:$ 1.46万
- 依托单位:
- 依托单位国家:加拿大
- 项目类别:Discovery Grants Program - Individual
- 财政年份:2016
- 资助国家:加拿大
- 起止时间:2016-01-01 至 2017-12-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Animal diseases have numerous economic and social impacts and are becoming an emerging global threat to the livestock industry and public health. An example is avian influenza, which has caused huge economic losses to the poultry industry globally and is a significant threat to public health. Understanding the mechanisms underlying the transmission of animal diseases is critical in preventing and managing disease outbreaks. An important route of animal disease transmission is airborne transmission by bioaerosols. In contrast to transmission by direct contact, airborne transmission is less understood and much more difficult to control. Airborne transmission of animal diseases is closely related to emission and dispersion of bioaerosols generated in animal operations. Bioaerosols are airborne particles originated from the fragmentation of biological materials or containing living organisms. In animal operations, bioaerosols are produced from animals, feed, bedding, and feces, and they consist of a complex mixture of biological, microbial, and inorganic particles. When emitted to the atmosphere, these bioaerosols act as a carrier for pathogens that travel in the air and may infect nearby animal facilities. A simple but critical research question is: how far can the pathogens associated with bioaerosols travel in the atmosphere and still be viable? The proposed research will explore the mechanisms by which pathogens are aerosolized in swine operations and an airborne transmission model will be developed for forecasting disease spread. The novelty of this research is to integrate biological models of pathogens with the theory of aerosol dispersion. PRRS (porcine reproductive and respiratory syndrome), which is an important swine disease that costs $130 million to the Canadian swine industry annually, will be studied as a model. The proposed research will provide a theoretical framework for developing tools for making control and eradication decisions in the event of an animal disease outbreak. This will benefit not only the livestock industry in Canada in terms of minimizing economic losses caused by animal diseases but also the general public in terms of reducing the risk of zoonotic disease transmission. Through the proposed research program, two (2) PhD, two (2) MSc and five (5) undergraduate students will be trained in a multidisciplinary environment involving integration of engineering with such biological sciences as animal science and microbiology. The research pogrom will also provide ample opportunities for the students to work with the livestock industry to prepare them for their future careers with the industry.
动物疾病具有许多经济和社会影响,正在成为畜牧业和公共卫生的一个新的全球威胁。禽流感就是一个例子,它给全球家禽业造成了巨大的经济损失,并对公共卫生构成重大威胁。了解动物疾病传播的机制对于预防和管理疾病暴发至关重要。动物疾病传播的一个重要途径是通过生物气溶胶进行空气传播。与直接接触传播相比,空气传播的了解较少,更难以控制。动物疾病的气载传播与动物操作过程中产生的生物气溶胶的排放和扩散密切相关。生物气溶胶是由生物材料的碎片或含有生物体的空气颗粒。在动物操作中,生物气溶胶由动物、饲料、垫料和粪便产生,它们由生物、微生物和无机颗粒的复杂混合物组成。当排放到大气中时,这些生物气溶胶作为病原体的载体在空气中传播,并可能感染附近的动物设施。一个简单但关键的研究问题是:与生物气溶胶相关的病原体在大气中传播多远并且仍然可行?拟议的研究将探索病原体在养猪场中雾化的机制,并将开发一个空气传播模型来预测疾病的传播。这项研究的新奇在于将病原体的生物模型与气溶胶扩散理论相结合。PRRS(猪繁殖与呼吸综合征)是一种重要的猪病,每年给加拿大养猪业造成1.3亿美元的损失,将作为模型进行研究。拟议的研究将提供一个理论框架,用于开发在动物疾病爆发时做出控制和根除决策的工具。这不仅有利于加拿大的畜牧业,减少动物疾病造成的经济损失,而且有利于公众减少人畜共患病传播的风险。通过拟议的研究计划,两(2)博士,两(2)硕士和五(5)本科生将在涉及工程与动物科学和微生物学等生物科学的整合的多学科环境中接受培训。研究大屠杀也将为学生提供充足的机会,与畜牧业工作,为他们未来的职业生涯做好准备。
项目成果
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专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Zhang, Qiang其他文献
Tourism experiences reduce the risk of cognitive impairment in the Chinese older adult: a prospective cohort study.
- DOI:
10.3389/fpubh.2023.1271319 - 发表时间:
2023 - 期刊:
- 影响因子:5.2
- 作者:
Li, Qian;Guo, Zheng;Hu, Fangli;Xiao, Mengfei;Zhang, Qiang;Wen, Jun;Ying, Tianyu;Zheng, Danni;Wang, Youxin;Yang, Song;Hou, Haifeng - 通讯作者:
Hou, Haifeng
Face recognition based on PCA image reconstruction and LDA
基于PCA图像重建和LDA的人脸识别
- DOI:
10.1016/j.ijleo.2013.04.108 - 发表时间:
2013-11 - 期刊:
- 影响因子:3.1
- 作者:
Zhou, Changjun;Wang, Lan;Zhang, Qiang;Wei, Xiaopeng - 通讯作者:
Wei, Xiaopeng
The Zn-Rich Corner of the Zn-Al-Fe-V Quaternary System at 450 A degrees C
450 A°C Zn-Al-Fe-V 四元系的富锌角
- DOI:
- 发表时间:
2012 - 期刊:
- 影响因子:1.4
- 作者:
Yin, Fucheng;Zhang, Qiang;Li, Zhi;Wang, Xinming;Zhao, Manxiu;Long, Zhaohui - 通讯作者:
Long, Zhaohui
A biomimetic nanovector-mediated targeted cholesterol-conjugated siRNA delivery for tumor gene therapy
仿生纳米载体介导的靶向胆固醇缀合 siRNA 递送用于肿瘤基因治疗。
- DOI:
10.1016/j.biomaterials.2012.08.057 - 发表时间:
2012-12-01 - 期刊:
- 影响因子:14
- 作者:
Ding, Yang;Wang, Wei;Zhang, Qiang - 通讯作者:
Zhang, Qiang
Novel self-healing dental resin with microcapsules of polymerizable triethylene glycol dimethacrylate and N,N-dihydroxyethyl-p-toluidine.
- DOI:
10.1016/j.dental.2015.11.014 - 发表时间:
2016-02 - 期刊:
- 影响因子:5
- 作者:
Wu, Junling;Weir, Michael D.;Zhang, Qiang;Zhou, Chuanjian;Melo, Mary Anne S.;Xu, Hockin H. K. - 通讯作者:
Xu, Hockin H. K.
Zhang, Qiang的其他文献
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{{ truncateString('Zhang, Qiang', 18)}}的其他基金
Air Ionization for Removal and Deactivation of Airborne Disease Pathogens in Animal Production Operations
空气电离用于去除和灭活动物生产操作中空气传播的疾病病原体
- 批准号:
RGPIN-2020-05691 - 财政年份:2022
- 资助金额:
$ 1.46万 - 项目类别:
Discovery Grants Program - Individual
Air Ionization for Removal and Deactivation of Airborne Disease Pathogens in Animal Production Operations
空气电离用于去除和灭活动物生产操作中空气传播的疾病病原体
- 批准号:
RGPIN-2020-05691 - 财政年份:2021
- 资助金额:
$ 1.46万 - 项目类别:
Discovery Grants Program - Individual
Air Ionization for Removal and Deactivation of Airborne Disease Pathogens in Animal Production Operations
空气电离用于去除和灭活动物生产操作中空气传播的疾病病原体
- 批准号:
RGPIN-2020-05691 - 财政年份:2020
- 资助金额:
$ 1.46万 - 项目类别:
Discovery Grants Program - Individual
Bioaerosols and airborne spread of diseases in animal production operations
动物生产作业中的生物气溶胶和疾病的空气传播
- 批准号:
RGPIN-2015-05965 - 财政年份:2019
- 资助金额:
$ 1.46万 - 项目类别:
Discovery Grants Program - Individual
Bioaerosols and airborne spread of diseases in animal production operations
动物生产作业中的生物气溶胶和疾病的空气传播
- 批准号:
RGPIN-2015-05965 - 财政年份:2018
- 资助金额:
$ 1.46万 - 项目类别:
Discovery Grants Program - Individual
Bioaerosols and airborne spread of diseases in animal production operations
动物生产作业中的生物气溶胶和疾病的空气传播
- 批准号:
RGPIN-2015-05965 - 财政年份:2017
- 资助金额:
$ 1.46万 - 项目类别:
Discovery Grants Program - Individual
Bioaerosols and airborne spread of diseases in animal production operations
动物生产作业中的生物气溶胶和疾病的空气传播
- 批准号:
RGPIN-2015-05965 - 财政年份:2015
- 资助金额:
$ 1.46万 - 项目类别:
Discovery Grants Program - Individual
SuperStraw for odour reduction in animal beddings
用于减少动物垫料气味的 SuperStraw
- 批准号:
465058-2014 - 财政年份:2014
- 资助金额:
$ 1.46万 - 项目类别:
Engage Grants Program
Pore structure and airflow resistance of bulk solids
散装固体的孔隙结构和气流阻力
- 批准号:
46215-2010 - 财政年份:2014
- 资助金额:
$ 1.46万 - 项目类别:
Discovery Grants Program - Individual
Pore structure and airflow resistance of bulk solids
散装固体的孔隙结构和气流阻力
- 批准号:
46215-2010 - 财政年份:2013
- 资助金额:
$ 1.46万 - 项目类别:
Discovery Grants Program - Individual
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