Pannexin 1 channels as novel regulators of malignant melanoma

Pannexin 1 通道作为恶性黑色素瘤的新型调节因子

• 批准号: 357424
• 负责人: Penuela Silvia
• 金额: $ 49.04万
• 依托单位: University of Western Ontario
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2016
• 资助国家: 加拿大
• 起止时间: 2016-10-01 至 2021-10-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=357424&lang=en
• 关键词: Cell Communication; Channels; Melanoma; Pannexin; Panx1; Skin; Skin Cancer; Trasgenic Mice; Tumour; Xenograft

Malignant melanoma is becoming more prevalent each year. Although it accounts for only 4% of all skin cancers, it is responsible for 79% of skin cancer-related deaths. There were 1,150 deaths from melanoma in Canada in 2015. Therefore, it is imperative to

恶性黑色素瘤每年变得越来越普遍。尽管它只占所有皮肤癌的 4%，但却造成了 79% 的皮肤癌相关死亡。 2015 年，加拿大有 1,150 人死于黑色素瘤。因此，当务之急是