Regulation and function of NFE2L3: linking transcription factor activity to tumorigenesis

NFE2L3 的调控和功能：将转录因子活性与肿瘤发生联系起来

• 批准号: 355816
• 负责人: Blank Volker
• 金额: $ 58.8万
• 依托单位: Lady Davis Institute for Medical Research (Mtl)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2016
• 资助国家: 加拿大
• 起止时间: 2016-10-01 至 2021-10-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=355816&lang=en
• 关键词: Cell Cycle; Cnc Proteins; Colorectal Cancer; Gene Regulation; Human Cancer Models; Mouse Models; Next Generation Sequencing; Protein-Protein Interactions; Transcription Factor; Tumorigenesis

Transcription factors are important molecules that control whether genes are active or not in a specific cell within an organism. Our research focuses on the functions of the CNC transcription factor family. Abnormal regulation of members of this group of

转录因子是控制基因在生物体内特定细胞中是否活跃的重要分子。我们的研究重点是cnc转录因子家族的功能。对这一组成员的不正常监管