Regulation of miR-626 Functions by Vesicant 3¿UTR

Vesicant 3UTR 对 miR-626 功能的调节

• 批准号: 182738
• 负责人: Yang Burton B
• 金额: $ 10.93万
• 依托单位: Sunnybrook Research Institute (Toronto, Ontario)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2009
• 资助国家: 加拿大
• 起止时间: 2009-03-01 至 2012-03-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=182738&lang=en
• 关键词: Gene Silencing; Hypoxia; Microrna; Myocardial Infarction; Stroke; Vascular Biology

Yang¿s group has established a transgenic line of mice expressing versican 3¿UTR. The hypothesis is that overexpression of versican 3¿UTR will bind and arrest endogenous miRNAs¿ functions. The inhibition of endogenous miRNA function frees the potential ta

Yang团队已经建立了一种表达变体3 - UTR的转基因小鼠系。假设是，过表达的versic3utr会结合并抑制内源性miRNAs的功能。内源性miRNA功能的抑制释放了ta的潜能