Accessing chromatin interactions by high-resolution analyses of correlated regulatory element variation

通过相关调控元件变异的高分辨率分析来了解染色质相互作用

• 批准号: 365032
• 负责人: Pastinen Tomi
• 金额: $ 58.28万
• 依托单位: McGill University
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-02-01 至 2020-02-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=365032&lang=en
• 关键词: Functional Genomics

Disease and development are reflected in chromatin states and their interactions in regulatory space. As opposed to developmental processes, it is anticipated that the genetic and epigenetic predisposition in disease is based on subtle alterations in chro

疾病和发育反映在染色质状态及其在调控空间中的相互作用中。与发育过程相反，预计疾病的遗传和表观遗传易感性是基于时间的细微改变