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Influence of pre-existing HIV cross-reactive CD4 T cells on vaccine responses to new Env immunogens

Influence of pre-existing HIV cross-reactive CD4 T cells on vaccine responses to new Env immunogens
现有 HIV 交叉反应 CD4 T 细胞对新 Env 免疫原疫苗反应的影响
批准号：
365740
负责人：
Kaufmann Daniel E
金额：
$18.21万
依托单位：
Centre hospitalier de l'Universit de Montral (CHUM)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2017
资助国家：
加拿大
项目状态：
已结题
起止时间：
2017-02-01 至 2018-08-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=365740&lang=en
关键词：
Antibody Cd4 T Cell Hiv Immune Repertoire Immunogen Design Immunogeneicity T Cell Memory Vaccine

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英文摘要
It is widely assumed that a successful HIV vaccine will elicit protective antibodies to prevent infection. The development of potent antibodies is regulated by a population of white blood cells called CD4 T cells. These CD4 T cells must recognize parts of
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