Predicting neurodevelopmental disorders from childhood trajectories of endophenotypes and genetic determinants in children born to an affected parent

从受影响父母所生儿童的内表型和遗传决定因素的童年轨迹预测神经发育障碍

• 批准号: 365235
• 负责人: Bureau Alexandre
• 金额: $ 14.53万
• 依托单位: Institut universitaire en sant mentale de Qubec (Qubec, QC)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-06-01 至 2019-06-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=365235&lang=en
• 关键词: Attenuated Symptoms; Bipolar Disorder; Cognition; Genetic Risk Score; Longitudinal Observations; Predictive Model; Schizophrenia

Schizophrenia and bipolar disorder affect 3% of our populations. The two disorders have common etiologies as expressed in shared common genetic determinants and clinical observations. This overlap now supports combining the disorders in risk and preventio

精神分裂症和双相情感障碍影响了3%的人口。这两种疾病有共同的病因，表现在共同的遗传决定因素和临床观察。这种重叠现在支持将疾病的风险和预防结合起来。