Tetrahydrobiopterin prevents coronary artery malformations induced by pregestational diabetes
Tetrahydrobiopterin prevents coronary artery malformations induced by pregestational diabetes
批准号:
368473
负责人:
Engineer Anish
金额:
$0.07万
依托单位国家:
加拿大
项目类别:
财政年份:
2017
资助国家:
加拿大
项目状态:
已结题
起止时间:
2017-07-01 至 2018-07-01
中文摘要
胚胎心脏冠状动脉的发育包括上皮细胞向间充质细胞的转化和细胞分化。我们之前已经表明,妊娠期糖尿病改变了基因表达、细胞迁移和增殖
英文摘要
Coronary artery development in the embryonic heart involves coordinated epithelial to mesenchymal transition (EMT) and cell differentiation. We have previously shown that pregestational maternal diabetes alters gene expression, cell migration and prolifer
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