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A systematic genome wide effort to identify and validate targetable synthetic dosage lethal interactions of mitotic kinases in colorectal cancer cells

A systematic genome wide effort to identify and validate targetable synthetic dosage lethal interactions of mitotic kinases in colorectal cancer cells
系统性全基因组工作,旨在识别和验证结直肠癌细胞中有丝分裂激酶的靶向合成剂量致死相互作用
批准号:
369423
负责人:
Vizeacoumar Franco J
金额:
$43.19万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2017
资助国家:
加拿大
项目状态:
已结题
起止时间:
2017-09-01 至 2022-09-01

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中文摘要
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英文摘要
Cancer cells often overexpress specific genes due to the effect of translocations, gene amplification, or other epigenetic modifications. Researchers have thought that directly inhibiting the function of these overexpressing genes could help to eliminate
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Identification of therapeutically relevant targets in telomerase overexpressing prostate cancers
  • 批准号:
    444391
  • 项目类别:
    Operating Grants
  • 资助金额:
    $71.61万
  • 财政年份:
    2021
  • 负责人:
    Vizeacoumar Franco J
  • 依托单位:
Systematic profiling of circular RNAs essential for the survival of cancer cells
  • 批准号:
    369561
  • 项目类别:
    Operating Grants
  • 资助金额:
    $41.8万
  • 财政年份:
    2017
  • 负责人:
    Vizeacoumar Franco J
  • 依托单位: