Characterization of Ars2 function in RNA processing

我的研究计划的长期目标是解决如何识别不同的RNA转录物家族并正确加工成具有不同目的地和功能的成熟RNA，并了解不同类型的RNA如何有助于干细胞和祖细胞行为。成熟RNA在细胞核中的产生是一个高度协调的多步骤过程，需要不同的复合物来进行不同RNA家族的生物发生。RNAPII转录物包括至少4种不同类型的RNA，每种都有自己的加工要求。RNAPII转录物的不同家族如何被识别和加工以产生成熟RNA尚不清楚。我的实验室发现了一种基因

The long term goal of my research program is to address how different families of RNA transcripts are recognized and correctly processed to mature RNAs with distinct destinations and functions and to understand how the different types of RNA contribute to stem and progenitor cell behavior. The generation of mature RNA in the nucleus is a highly coordinated multistep process that requires distinct complexes for the biogenesis of different RNA families. RNAPII transcripts include at least 4 different types of RNA, each with its own processing requirements. How different families of RNAPII transcripts are recognized and processed to generate mature RNA is not understood. My lab discovered a gene called