The origin and compartmentalization of core somatic histones and GSTO2 in sperm and their role in fertilization

精子中核心体细胞组蛋白和 GSTO2 的起源和划分及其在受精中的作用

• 批准号: RGPIN-2017-05305
• 负责人: Oko, Richard
• 金额: $ 2.91万
• 依托单位: Queen's University
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=629367
• 关键词: origin; compartmentalization; core; somatic; histones

Fertilization is the cornerstone of development where the two differentiated cells, sperm and egg, set the stage for embryogenesis, for which competency of the gametes is essential. Yet only rudimentary knowledge is available on the molecules and mechanisms involved in sperm-egg interactions leading to zygotic development.

受精是发育的基石，其中两个分化的细胞，精子和卵子，为胚胎发生奠定了基础，配子的能力是必不可少的。然而，只有基本的知识是可利用的分子和机制，涉及精卵相互作用，导致合子的发展。