Compartmented cAMP signalling Regulates Human Arterial Endothelial Cell Inflammatory and Angiogenic Responses

区室 cAMP 信号传导调节人动脉内皮细胞炎症和血管生成反应

• 批准号: 369092
• 负责人: Maurice Donald H
• 金额: $ 49.6万
• 依托单位: Queen's University (Kingston, Ontario)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-09-01 至 2022-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=369092&lang=en
• 关键词: Angiogenesis; Athersoclerosis; Camp Signalling; Cyclic Nucleotide Phosphodiesterases; Endothelial Cells; Phosphodiesterase Inhibitors; Sepsis; Vascular Biology

Blood vessels in a healthy adult are stable and do not change very much. When diseases affect blood vessels, the cells that are contained in blood vessels can change. While most of these changes tend to be positive, and related to healing the damage, some

健康成年人的血管是稳定的，不会有太大的变化。当疾病影响血管时，血管中包含的细胞会发生变化。虽然这些变化大多是积极的，与修复损伤有关，但也有一些