DBL protein function in Plasmodium chabaudi invasion and cytoadhesion

DBL 蛋白在恰鲍迪疟原虫侵袭和细胞粘附中的功能

• 批准号: RGPIN-2017-04176
• 负责人: Yanow, Stephanie
• 金额: $ 1.89万
• 依托单位: University of Alberta
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=629651
• 关键词: DBL; protein; function; Plasmodium; chabaudi

Plasmodium (P.) is a parasite that has evolved over millions of years and causes malaria in a range of animal hosts. There are six species that infect humans and over two hundred other species that infect animals, including rodents and monkeys, which are commonly used as models to study basic parasite biology and immunology. The effects of Plasmodium on these hosts vary from benign to lethal infections, depending on parasite genetics and the ability of the host to respond to infection.

疟原虫（P.）是一种经过数百万年进化的寄生虫，在一系列动物宿主中引起疟疾。有六种感染人类的物种和超过200种感染动物的物种，包括啮齿动物和猴子，它们通常被用作研究基本寄生虫生物学和免疫学的模型。疟原虫对这些宿主的影响从良性到致命感染不等，这取决于寄生虫遗传学和宿主对感染的反应能力。