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Elucidating novel mechanisms of extracellular nucleic acid recognition, internalization, trafficking and signaling: implications for infection, inflammation and autoimmunity.

Elucidating novel mechanisms of extracellular nucleic acid recognition, internalization, trafficking and signaling: implications for infection, inflammation and autoimmunity.
阐明细胞外核酸识别、内化、运输和信号传导的新机制:对感染、炎症和自身免疫的影响。
批准号:
368171
负责人:
Mossman Karen L
金额:
$54.34万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2017
资助国家:
加拿大
项目状态:
已结题
起止时间:
2017-09-01 至 2022-09-01

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中文摘要
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英文摘要
Extracellular or circulating nucleic acids derived from infected or damaged cells can be of virus or self origin. Once recognized and taken up by healthy cells, these nucleic acids rapidly and potently lead to the production of cytokines, including interf
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EDI Stipend
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Elucidating the molecular mechanism by which bat IRFs modulate antiviral responses
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Understanding susceptibility and permissiveness to mpox virus across diverse mammalian species
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Elucidating the molecular mechanism by which bat Interferon Regulatory Factors modulate antiviral responses
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    484177
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海外基金