Protein-protein and protein-peptidoglycan interactions leading to assembly of the Type II secretion system

蛋白质-蛋白质和蛋白质-肽聚糖相互作用导致 II 型分泌系统的组装

• 批准号: RGPIN-2017-04777
• 负责人: Howard, Stephen
• 金额: $ 1.89万
• 依托单位: University of Saskatchewan
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=629728
• 关键词: Protein; protein; peptidoglycan; interactions; leading

The research of our laboratory is concerned with the structure and function of the two membranes that surround the cells of a major class of bacteria known as the Gram-negatives. We study interactions between the inner and outer membrane as well as the transport of materials across the outer membrane. This transport is a fundamental life process because membranes act as a barrier in protecting all living cells from the environment, but that barrier must be overcome so that nutrients and proteins required for life can cross them.

我们实验室的研究关注的是围绕一个主要类别的细菌称为革兰氏阴性菌的细胞的两个膜的结构和功能。我们研究了内外膜之间的相互作用以及物质穿过外膜的运输。这种运输是一个基本的生命过程，因为膜作为一个屏障，保护所有活细胞免受环境的影响，但必须克服这一屏障，使生命所需的营养物质和蛋白质可以穿过它们。