The influence of bacterial lipid composition variation on transporter function and folding.

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Bacterial species diversity is vast and the wide variety and distribution of lipids that reside in their membranes highlights this diversity. Lipids are hydrophobic chemicals that can vary in chain length, saturation, branching and head group charge; all of which result in changes in membrane thickness, net charge and fluidity. Lipid variation has can also be used as a way to classify and distinguish bacterial species from one another. Despite this knowledge, our understanding of how lipids influence the function of bacterial membranes remains poorly understood.