Understanding the roles of diacylglycerol acyltransferases in triacylglycerol biosynthesis and storage

了解二酰甘油酰基转移酶在三酰甘油生物合成和储存中的作用

• 批准号: RGPIN-2017-04355
• 负责人: stone, scot
• 金额: $ 2.48万
• 依托单位: University of Saskatchewan
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=630059
• 关键词: Understanding; roles; diacylglycerol; acyltransferases; triacylglycerol

Triacylglycerol (TG) is quantitatively the most important storage form of metabolic energy for most living organisms. TGs consist of a glycerol backbone to which three fatty acids are attached. Because they are highly reduced and anhydrous, TGs are capable of providing much more energy than carbohydrate or protein. Eukaryotic organisms store TGs in cytosolic lipid droplets that can be metabolized during periods of nutrient deprivation when energy requirements are not being satisfied. Plants store large quantities of TGs in seeds that are used as energy for seedling growth and development.

甘油三酯（TG）是大多数生物体内最重要的代谢能量储存形式。tg由甘油主链和三种脂肪酸组成。因为它们是高度还原和无水的，tg能够提供比碳水化合物或蛋白质更多的能量。真核生物将tg储存在胞质脂滴中，当能量需求得不到满足时，这些脂滴可以在营养剥夺期间被代谢掉。植物在种子中储存大量的TGs，作为幼苗生长发育的能量。