Improving Corneal Endothelial Cell Adhesion

改善角膜内皮细胞粘附

• 批准号: 368194
• 负责人: Casey Joseph (Joe) R
• 金额: $ 69.11万
• 依托单位: University of Alberta
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-09-01 至 2022-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=368194&lang=en
• 关键词: Cell Adhesion; Congenital Hereditary Endothelial Dystrophy; Cornea; Corneal Dystrophy; Descemet'S Membrane; Fuchs Endothelial Corneal Dystrophy; Mouse Model; Slc4a11; Viral Transduction

Fuchs endothelial corneal dystrophy is a genetic disease of the inner layer of the cornea, called the endothelium. It affects 4% of people to various degrees in their lifetime. Symptoms are progressive, leading to severe eye pain and cloudy vision if left

富克斯角膜内皮营养不良是一种遗传性疾病的内层角膜，称为内皮。4%的人在一生中受到不同程度的影响。症状是渐进的，导致严重的眼睛疼痛和浑浊的视力，如果离开