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The gut epithelium as a target organ of ingested metals: investigating Cd-induced ERK activation and the related impatcs on intestinal function in vitro and in vivo

The gut epithelium as a target organ of ingested metals: investigating Cd-induced ERK activation and the related impatcs on intestinal function in vitro and in vivo
肠道上皮作为摄入金属的靶器官:研究镉诱导的 ERK 激活及其对体外和体内肠道功能的相关影响
批准号:
RGPIN-2017-05106
负责人:
Jumarie, Catherine
金额:
$1.82万
依托单位国家:
加拿大
项目类别:
Discovery Grants Program - Individual
财政年份:
2017
资助国家:
加拿大
项目状态:
已结题
起止时间:
2017-01-01 至 2018-12-31

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中文摘要
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英文摘要
Cadmium (Cd) is a toxic metal with many industrial uses that is present in atmosphere, run off water, soil and sediment. It is absorbed through inhalation (in work places and for tobacco smokers), and ingestion of contaminated food products. Cadmium is poorly eliminated and it remains in the body. Its toxicity includes pulmonary obstructive diseases, kidney dysfunction, and osteomalacia (bones softening). Cd is also a carcinogen. It is listed by the US Environmental Protection Agency as well as by Environment and Health Canada as one of priority pollutants.
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The gut epithelium as a target organ of ingested metals: investigating Cd-induced ERK activation and the related impatcs on intestinal function in vitro and in vivo
  • 批准号:
    RGPIN-2017-05106
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $1.82万
  • 财政年份:
    2020
  • 负责人:
    Jumarie, Catherine
  • 依托单位:
The gut epithelium as a target organ of ingested metals: investigating Cd-induced ERK activation and the related impatcs on intestinal function in vitro and in vivo
  • 批准号:
    RGPIN-2017-05106
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $1.82万
  • 财政年份:
    2019
  • 负责人:
    Jumarie, Catherine
  • 依托单位:
The gut epithelium as a target organ of ingested metals: investigating Cd-induced ERK activation and the related impatcs on intestinal function in vitro and in vivo
  • 批准号:
    RGPIN-2017-05106
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $1.82万
  • 财政年份:
    2018
  • 负责人:
    Jumarie, Catherine
  • 依托单位:
Intestinal exposure to metals: impact on cell differentiation and intestinal cell funtions.
  • 批准号:
    203202-2011
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $1.75万
  • 财政年份:
    2015
  • 负责人:
    Jumarie, Catherine
  • 依托单位:
国内基金
海外基金
嗅觉信号转导及功能障碍的研究
  • 批准号:
    30672303
  • 项目类别:
    面上项目
  • 资助金额:
    28.0万元
  • 批准年份:
    2006
  • 负责人:
    魏永祥
  • 依托单位: