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Reinforcing Properties of Wheel Running

车轮运行的增强性能

基本信息

批准号：
170022-2013
负责人：
Belke, Terry
金额：
$ 1.74万
依托单位：
Mount Allison University
依托单位国家：
加拿大
项目类别：
Discovery Grants Program - Individual
财政年份：
2017
资助国家：
加拿大
起止时间：
2017-01-01 至 2018-12-31
项目状态：
已结题

来源：
https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=631489
关键词：
Reinforcing Properties Wheel Running

项目摘要

Physical inactivity is considered a major public health issue in that inactivity contributes significantly to risk of death from heart disease, diabetes, and cancer. Addressing this issue requires increased participation in exercise by the general population. While this goal is easy to state, it has proven difficult to accomplish. Learning more about the rewarding properties of physical activity and factors that influence motivation to engage in physical activity may prove useful with respect to accomplishing this goal. My research program addresses this issue by studying the conditions that influence motivation to run in an animal model. In my lab, rats work, by pressing a lever, to obtain an opportunity to run in a wheel. The more motivated the rats are to run or the more rewarding running is for the rats, the harder they tend to work for that opportunity to run. The properties of running as a reward and the conditions that influence its rewarding value are not was well known as those for food and water. How do they differ from, and in what ways are they similar to, the rewarding value of food and water? In my research program, I will explore how the value of running may change with duration that a rat is given to run, how extrinsic incentives for running may affect the intrinsic rewarding effects of running, and if running when rats are not weight controlled is similar to that when rats are weight controlled.

缺乏身体活动被认为是一个主要的公共卫生问题，因为缺乏活动会显著增加心脏病、糖尿病和癌症的死亡风险。解决这一问题需要广大民众更多地参与体育活动。虽然这一目标很容易陈述，但事实证明很难实现。更多地了解体育活动的有益特性以及影响参与体育活动动机的因素可能对实现这一目标有用。我的研究项目通过研究影响动物模型中跑步动机的条件来解决这个问题。在我的实验室里，老鼠通过按压杠杆来获得在轮子上跑步的机会。老鼠跑步的动机越强，或者跑步对老鼠的回报越大，它们就越努力争取跑步的机会。跑步作为奖励的性质和影响其奖励价值的条件并不像食物和水那样为人所熟知。它们与食物和水的回报价值有何不同，又有哪些相似之处？在我的研究计划中，我将探索跑步的价值如何随着大鼠跑步的持续时间而变化，跑步的外在激励如何影响跑步的内在奖励效应，以及当大鼠不控制体重时跑步是否与控制体重时相似。