Exploiting Neglected Reactivity to Develop New Tools for Organic Synthesis and Medicinal Chemistry
利用被忽视的反应性开发有机合成和药物化学的新工具
基本信息
- 批准号:RGPIN-2017-05677
- 负责人:
- 金额:$ 3.28万
- 依托单位:
- 依托单位国家:加拿大
- 项目类别:Discovery Grants Program - Individual
- 财政年份:2017
- 资助国家:加拿大
- 起止时间:2017-01-01 至 2018-12-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Our research focuses on finding new and improved ways of making value-added organic molecules from simple chemical feedstocks. Although the new technology we develop will most directly impact the discovery and development of pharmaceuticals, the fundamental knowledge gained in the process will be broadly useful. Specifically, we aim to take poorly understood and undeveloped chemical processes and transform them into practical methods to make useful organic compounds. With this as a guiding principle we will tackle the following challenges:
我们的研究重点是寻找新的和改进的方法,从简单的化学原料中制造增值的有机分子。虽然我们开发的新技术将最直接地影响药物的发现和开发,但在此过程中获得的基础知识将广泛有用。具体来说,我们的目标是采取不太了解和未开发的化学过程,并将其转化为实用的方法,使有用的有机化合物。以此为指导原则,我们将应对以下挑战:
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Orellana, Arturo其他文献
Palladium-Catalyzed Selective Carboelimination and Cross-Coupling Reactions of Benzocyclobutenols with Aryl Bromides
- DOI:
10.1021/jo201632c - 发表时间:
2011-11-04 - 期刊:
- 影响因子:3.6
- 作者:
Chtchemelinine, Andrei;Rosa, David;Orellana, Arturo - 通讯作者:
Orellana, Arturo
Alkylidene Dihydropyridines Are Surrogates for Pyridylic Anions in the Conjugate Addition to α,β-Unsaturated Ketones
- DOI:
10.1021/acs.orglett.1c03615 - 发表时间:
2021-12-10 - 期刊:
- 影响因子:5.2
- 作者:
Shi, Jiaqi;Sayyad, Ashik;Orellana, Arturo - 通讯作者:
Orellana, Arturo
The Acid-Free Cyclopropanol-Minisci Reaction Reveals the Catalytic Role of Silver-Pyridine Complexes
- DOI:
10.1021/acs.orglett.7b03938 - 发表时间:
2018-02-02 - 期刊:
- 影响因子:5.2
- 作者:
Nikolaev, Andrei;Legault, Claude Y.;Orellana, Arturo - 通讯作者:
Orellana, Arturo
Synthesis of Acyl Pyrroles via Palladium-Catalyzed Carbonylative Amination of Aryl and Alkenyl Iodides
- DOI:
10.1021/jo2022444 - 发表时间:
2012-02-17 - 期刊:
- 影响因子:3.6
- 作者:
Ho, Stephanie;Bondarenko, Ganna;Orellana, Arturo - 通讯作者:
Orellana, Arturo
Towards the total synthesis of FD-838: modular enantioselective assembly of the core
- DOI:
10.1039/b716445a - 发表时间:
2008-01-01 - 期刊:
- 影响因子:4.9
- 作者:
Orellana, Arturo;Rovis, Tomislav - 通讯作者:
Rovis, Tomislav
Orellana, Arturo的其他文献
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{{ truncateString('Orellana, Arturo', 18)}}的其他基金
Exploiting Neglected Reactivity to Develop New Tools for Organic Synthesis and Medicinal Chemistry
利用被忽视的反应性开发有机合成和药物化学的新工具
- 批准号:
RGPIN-2017-05677 - 财政年份:2022
- 资助金额:
$ 3.28万 - 项目类别:
Discovery Grants Program - Individual
Exploiting Neglected Reactivity to Develop New Tools for Organic Synthesis and Medicinal Chemistry
利用被忽视的反应性开发有机合成和药物化学的新工具
- 批准号:
RGPIN-2017-05677 - 财政年份:2021
- 资助金额:
$ 3.28万 - 项目类别:
Discovery Grants Program - Individual
Exploiting Neglected Reactivity to Develop New Tools for Organic Synthesis and Medicinal Chemistry
利用被忽视的反应性开发有机合成和药物化学的新工具
- 批准号:
RGPIN-2017-05677 - 财政年份:2020
- 资助金额:
$ 3.28万 - 项目类别:
Discovery Grants Program - Individual
Cross-Coupling Reactions Leading to Chiral Heterocyclic Scaffolds for Drug Development and Manufacturing
交叉偶联反应产生用于药物开发和制造的手性杂环支架
- 批准号:
536415-2018 - 财政年份:2019
- 资助金额:
$ 3.28万 - 项目类别:
Collaborative Research and Development Grants
Exploiting Neglected Reactivity to Develop New Tools for Organic Synthesis and Medicinal Chemistry
利用被忽视的反应性开发有机合成和药物化学的新工具
- 批准号:
RGPIN-2017-05677 - 财政年份:2019
- 资助金额:
$ 3.28万 - 项目类别:
Discovery Grants Program - Individual
Exploiting Neglected Reactivity to Develop New Tools for Organic Synthesis and Medicinal Chemistry
利用被忽视的反应性开发有机合成和药物化学的新工具
- 批准号:
RGPIN-2017-05677 - 财政年份:2018
- 资助金额:
$ 3.28万 - 项目类别:
Discovery Grants Program - Individual
Palladium-Catalyzed Reactions Using C-C Bond Activation of Strained Tertiary Alcohols and their Applications in Complex Molecule Synthesis
钯催化的叔醇 C-C 键活化反应及其在复杂分子合成中的应用
- 批准号:
355547-2012 - 财政年份:2016
- 资助金额:
$ 3.28万 - 项目类别:
Discovery Grants Program - Individual
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