Stereoselective Process involving radicals. Synthesis and Methodology.
涉及自由基的立体选择性过程。
基本信息
- 批准号:RGPIN-2015-06405
- 负责人:
- 金额:$ 3.28万
- 依托单位:
- 依托单位国家:加拿大
- 项目类别:Discovery Grants Program - Individual
- 财政年份:2017
- 资助国家:加拿大
- 起止时间:2017-01-01 至 2018-12-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
One of the long-term objectives of our research program is to contribute from a strategic and theoretical standpoint with approaches leading to the creation of new stereogenic centers on acyclic molecules. Of particular interest to us is the development of approaches involving free radical intermediates. These studies have already led to the development of various tools, which we plan to use in the synthesis of natural products of biological interest or analogues thereof, as part of our medicinal chemistry efforts.
我们研究计划的长期目标之一是从战略和理论的角度出发,为在无环分子上创建新的立体中心做出贡献。我们特别感兴趣的是涉及自由基中间体的方法的发展。这些研究已经导致了各种工具的开发,我们计划将其用于合成具有生物学意义的天然产物或其类似物,作为我们药物化学工作的一部分。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Guindon, Yvan其他文献
Stereocontrolled Synthesis of C1-C17 Fragment of Narasin via a Free Radical-Based Approach
- DOI:
10.1021/ol902414u - 发表时间:
2010-01-01 - 期刊:
- 影响因子:5.2
- 作者:
Brazeau, Jean-Francois;Guilbault, Audrey-Anne;Guindon, Yvan - 通讯作者:
Guindon, Yvan
Stereopentads Derived from a Sequence of Mukaiyama Aldolization and Free Radical Reduction on α-Methyl-β-alkoxy Aldehydes: A General Strategy for Efficient Polypropionate Synthesis
- DOI:
10.1021/jo8021583 - 发表时间:
2009-01-02 - 期刊:
- 影响因子:3.6
- 作者:
Brazeau, Jean-Francois;Mochrian, Philippe;Guindon, Yvan - 通讯作者:
Guindon, Yvan
Synthesis of 1′,2′-cis-Nucleoside Analogues: Evidence of Stereoelectronic Control for SN2 Reactions at the Anomeric Center of Furanosides
- DOI:
10.1021/ja104429y - 发表时间:
2010-09-08 - 期刊:
- 影响因子:15
- 作者:
Prevost, Michel;St-Jean, Olivier;Guindon, Yvan - 通讯作者:
Guindon, Yvan
Acyclic Tethers Mimicking Subunits of Polysaccharide Ligands: Selectin Antagonists
- DOI:
10.1021/ml500266x - 发表时间:
2014-09-01 - 期刊:
- 影响因子:4.2
- 作者:
Calosso, Mickael;Tambutet, Guillaume;Guindon, Yvan - 通讯作者:
Guindon, Yvan
Dual-Face Nucleoside Scaffold Featuring a Stereogenic All-Carbon Quaternary Center. Intramolecular Silicon Tethered Group-Transfer Reaction
- DOI:
10.1021/ol502777r - 发表时间:
2014-11-07 - 期刊:
- 影响因子:5.2
- 作者:
Tambutet, Guillaume;Becerril-Jimenez, Fabiola;Guindon, Yvan - 通讯作者:
Guindon, Yvan
Guindon, Yvan的其他文献
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{{ truncateString('Guindon, Yvan', 18)}}的其他基金
Reaction Mechanisms and Methodology for the Design and Synthesis of Bioactive Agents.
生物活性剂设计和合成的反应机制和方法。
- 批准号:
RGPIN-2020-06507 - 财政年份:2022
- 资助金额:
$ 3.28万 - 项目类别:
Discovery Grants Program - Individual
Reaction Mechanisms and Methodology for the Design and Synthesis of Bioactive Agents.
生物活性剂设计和合成的反应机制和方法。
- 批准号:
RGPIN-2020-06507 - 财政年份:2021
- 资助金额:
$ 3.28万 - 项目类别:
Discovery Grants Program - Individual
Reaction Mechanisms and Methodology for the Design and Synthesis of Bioactive Agents.
生物活性剂设计和合成的反应机制和方法。
- 批准号:
RGPIN-2020-06507 - 财政年份:2020
- 资助金额:
$ 3.28万 - 项目类别:
Discovery Grants Program - Individual
Stereoselective Process involving radicals. Synthesis and Methodology.
涉及自由基的立体选择性过程。
- 批准号:
RGPIN-2015-06405 - 财政年份:2019
- 资助金额:
$ 3.28万 - 项目类别:
Discovery Grants Program - Individual
Stereoselective Process involving radicals. Synthesis and Methodology.
涉及自由基的立体选择性过程。
- 批准号:
RGPIN-2015-06405 - 财政年份:2018
- 资助金额:
$ 3.28万 - 项目类别:
Discovery Grants Program - Individual
Stereoselective Process involving radicals. Synthesis and Methodology.
涉及自由基的立体选择性过程。
- 批准号:
RGPIN-2015-06405 - 财政年份:2016
- 资助金额:
$ 3.28万 - 项目类别:
Discovery Grants Program - Individual
Stereoselective Process involving radicals. Synthesis and Methodology.
涉及自由基的立体选择性过程。
- 批准号:
RGPIN-2015-06405 - 财政年份:2015
- 资助金额:
$ 3.28万 - 项目类别:
Discovery Grants Program - Individual
Stereoselective process involving radicals; synthesis and methodology
涉及自由基的立体选择性过程;
- 批准号:
184027-2010 - 财政年份:2014
- 资助金额:
$ 3.28万 - 项目类别:
Discovery Grants Program - Individual
Stereoselective process involving radicals; synthesis and methodology
涉及自由基的立体选择性过程;
- 批准号:
184027-2010 - 财政年份:2013
- 资助金额:
$ 3.28万 - 项目类别:
Discovery Grants Program - Individual
Stereoselective process involving radicals; synthesis and methodology
涉及自由基的立体选择性过程;
- 批准号:
184027-2010 - 财政年份:2012
- 资助金额:
$ 3.28万 - 项目类别:
Discovery Grants Program - Individual
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Stereoselective Process involving radicals. Synthesis and Methodology.
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Discovery Grants Program - Individual
Stereoselective process involving radicals; synthesis and methodology
涉及自由基的立体选择性过程;
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Discovery Grants Program - Individual
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涉及自由基的立体选择性过程;
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