Enhancing high intensity focused ultrasound molecule delivery using molecular imaging

使用分子成像增强高强度聚焦超声分子传递

• 批准号: RGPIN-2015-05197
• 负责人: Curiel, Laura
• 金额: $ 1.11万
• 依托单位: Lakehead University
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=632954
• 关键词: Enhancing; intensity; focused; ultrasound; molecule

Sponges absorb water because they contain thousands of small pores – expand the pores, and they’ll absorb more water. Tissues in the body can act in a similar way. Tumours treated with chemotherapy absorb the drug, destroying the cancer cells. What if there was a method to expand tissue pores to increase absorption and in turn effectiveness? What if this method could help go through natural blockages such as the blood-brain barrier?

海绵吸水是因为它们含有成千上万的小毛孔——扩大毛孔，它们就会吸收更多的水。人体组织也可以以类似的方式运作。用化疗治疗的肿瘤会吸收药物，摧毁癌细胞。如果有一种方法可以扩大组织毛孔来增加吸收，进而提高效率呢？如果这种方法可以帮助穿过血脑屏障等自然阻塞，会怎么样呢？