Advanced Bioreactors for Evaluation and Systematic Optimization of Decellularization and Recellularization of the Lung and Trachea

用于肺和气管脱细胞和再细胞化评估和系统优化的先进生物反应器

• 批准号: 376742
• 负责人: Amon Cristina
• 金额: $ 21.26万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-11-01 至 2020-11-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=376742&lang=en
• 关键词: Airway Regeneration; Biological Scaffolds; Bioreactor; Decellularization; In Silico Modelling; Lung; Recellularization; Systematic Process Optimization; Tissue Engineering; Trachea

Diseases affecting the airways are an important clinical problem and for the majority of patients with end-stage disease, transplantation of lung and/or trachea has become the only life-saving option. Ideally we need access to 'off-the-shelf' replacement

影响气道的疾病是一个重要的临床问题，对于大多数终末期疾病患者，肺和/或气管移植已成为挽救生命的唯一选择。理想情况下，我们需要获得“现成”的替代品