Defining the role of ArpC1b and the actin cytoskeleton in macrophage migration, phagocytosis, and immunoregulation

定义 ArpC1b 和肌动蛋白细胞骨架在巨噬细胞迁移、吞噬作用和免疫调节中的作用

• 批准号: 383379
• 负责人: Ostrowski Philip
• 金额: $ 7.65万
• 依托单位: Hospital for Sick Children (Toronto)
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-10-01 至 2020-10-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=383379&lang=en
• 关键词: Autoimmunity; Autoinflammation; Cell Migration; Macrophage And Immunity; Phagocytosis; Podosome

Macrophages are cells present in virtually every organ, where they play an important role in both the short-term (innate) and long-term (adaptive) immune responses. They can engulf foreign pathogens as well as clear the millions of dead cells produced by

巨噬细胞是几乎存在于每个器官中的细胞，它们在短期(先天)和长期(适应性)免疫反应中都发挥着重要作用。它们可以吞噬外来病原体，也可以清除由