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A multi-phase clinical trial to establish biological proof-of-concept, determine safety and maximum tolerated dose, and assess efficacy of neoadjuvant ketoconazole and posaconazole in patients with recurrent high grade gliomas

A multi-phase clinical trial to establish biological proof-of-concept, determine safety and maximum tolerated dose, and assess efficacy of neoadjuvant ketoconazole and posaconazole in patients with recurrent high grade gliomas
一项多阶段临床试验,旨在建立生物学概念验证,确定安全性和最大耐受剂量,并评估酮康唑和泊沙康唑新辅助治疗复发性高级别胶质瘤患者的疗效
批准号:
377221
负责人:
Mansouri Alireza
金额:
$16.03万
依托单位国家:
加拿大
项目类别:
Fellowship Programs
财政年份:
2017
资助国家:
加拿大
项目状态:
已结题
起止时间:
2017-11-01 至 2021-11-01

项目摘要

项目成果

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中文摘要
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英文摘要
High grade gliomas (HGGs) are the most common and aggressive brain tumors. Among many aggressive features, they invade much farther into the brain than we can see with MRI or the microscope and so surgeons can never remove the entire tumor. That is why ra
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