The physiological role of rhomboid-like protein 4 in Alzheimer's disease pathology

类菱形蛋白4在阿尔茨海默病病理学中的生理作用

• 批准号: 386327
• 负责人: Recinto Sherilyn Junelle
• 金额: $ 1.27万
• 依托单位: McGill University
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-12-01 至 2018-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=386327&lang=en
• 关键词: Amyloid Precursor Protein; Cell Culture Experiments (In-Vitro Studies); Cloning; Immunocytochemistry/Immunohistochemistry; In-Vivo Studies; Intramembrane Proteolysis; Non-Amyloidogenic Pathways; Regulatory Mechanism; Rhomboid Protease; Western Blot

A total of 36 million people worldwide is affected by Alzheimer's disease (AD), a debilitating neurodegenerative disease primarily characterized by worsening memory impairments as diseased stage advances. To date, no effective or preventative treatments a

全世界共有3600万人受到阿尔茨海默病（AD）的影响，这是一种使人衰弱的神经退行性疾病，其主要特征是随着疾病阶段的进展而恶化的记忆障碍。到目前为止，没有有效的或预防性的治疗方法，