The Role of Minocycline in Attenuating Neuronal Swelling

米诺环素在减轻神经元肿胀中的作用

• 批准号: 386532
• 负责人: Sack Anne-Sophie
• 金额: $ 1.27万
• 依托单位: University of British Columbia
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-12-01 至 2018-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=386532&lang=en
• 关键词: Chimera; Cytotoxic Edema; Minocycline; Neuronal Swelling; Neuroprotection; Slc26a11; Traumatic Brain Injury; Veratridine; Voltage-Gated Chloride Transporter

Brain swelling can be classified as cytotoxic edema, where swelling of cellular elements subsequently lead to cell death.Recently, the role of a voltage-gated chloride transporter, called SLC26A11, has been identified in mediating cytotoxic edema.Given th

脑肿胀可归类为细胞毒性水肿，其中细胞成分的肿胀随后导致细胞死亡。最近，已确定电压门控氯转运蛋白（称为 SLC26A11）在介导细胞毒性水肿中的作用。