Fluid flow Promotion of the Healthy State: Technology Platforms and Mechanisms

流体流动促进健康状态：技术平台与机制

• 批准号: RGPIN-2017-04870
• 负责人: Rinker, Kristina
• 金额: $ 1.75万
• 依托单位: University of Calgary
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=637954
• 关键词: Fluid; flow; Promotion; Healthy; State

Work in my lab is focused upon creating tissue models mimicking fluid forces aspects of the in vivo state of various tissues. These models can be used for testing cell and tissue physiology, discovering key modulators of cell function, and developing a mechanistic understanding of tissue function under flow. We have translated discoveries and platform technologies based on these concepts with submission of multiple patent applications, formation of 4 companies, and multiple trainees employed in the engineering and technology sectors in the past five years. Over the next five to ten years we propose to continue developing platform technologies and knowledge in mechanobiology to facilitate advances in health and technology.

在我的实验室工作的重点是创建组织模型模仿流体力方面的各种组织的体内状态。这些模型可用于测试细胞和组织生理学，发现细胞功能的关键调节剂，并开发流动下组织功能的机械理解。在过去的五年里，我们已经根据这些概念翻译了发现和平台技术，提交了多项专利申请，成立了4家公司，并在工程和技术领域雇用了多名培训生。在接下来的五到十年里，我们建议继续开发机械生物学的平台技术和知识，以促进健康和技术的进步。