Fluid flow Promotion of the Healthy State: Technology Platforms and Mechanisms

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Work in my lab is focused upon creating tissue models mimicking fluid forces aspects of the in vivo state of various tissues. These models can be used for testing cell and tissue physiology, discovering key modulators of cell function, and developing a mechanistic understanding of tissue function under flow. We have translated discoveries and platform technologies based on these concepts with submission of multiple patent applications, formation of 4 companies, and multiple trainees employed in the engineering and technology sectors in the past five years. Over the next five to ten years we propose to continue developing platform technologies and knowledge in mechanobiology to facilitate advances in health and technology.