Cellular Fatty Acid Uptake by CD36: Identifying Amino Acids That Play a Critical Role Through Site Directed Mutagenesis and in vitro Assays

CD36 的细胞脂肪酸摄取：通过定点诱变和体外测定鉴定发挥关键作用的氨基酸

• 批准号: 386512
• 负责人: Piche Julia E
• 金额: $ 1.27万
• 依托单位: University of Alberta
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-12-01 至 2018-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=386512&lang=en
• 关键词: Cd36; Fatty Acid Uptake; In Vitro; Mediated Transport; Metabolism; Protein Mechanism

The ability of cells to uptake fatty acids is essential for cellular function and abnormalities in this process could have significant health effects. Flip-flop across a membrane and/or transport via a class of proteins known as fatty acid transport prote

细胞摄取脂肪酸的能力对细胞功能至关重要，这一过程中的异常可能会对健康产生重大影响。翻转通过膜和/或通过一类称为脂肪酸转运蛋白的蛋白质进行转运