Design of orthopedic implants made of porous metallic materials using additive manufacturing technologies

使用增材制造技术设计由多孔金属材料制成的骨科植入物

• 批准号: RGPIN-2017-05958
• 负责人: Nuño, Natalia
• 金额: $ 1.82万
• 依托单位: École de technologie supérieure
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=638525
• 关键词: Design; orthopedic; implants; made; porous

Long-term survivorship of orthopedic implants remains a challenge as patients are becoming younger and more active. One factor compromising the longevity of the implant is bone resorption believed to be due to stress shielding. Bone is a living tissue and reacts to its mechanical stimuli. When bone is removed to be replaced by an artificial implant, a redistribution of the stresses within the bone occurs. This stress shielding phenomenon occurs because of the large difference in rigidity between the metallic implant and the surrounding bone. The bone is thus stress shielded, consequently the bone is resorbed and its density decreased, eventually leading to failure of the arthroplasty. New materials are needed to mimic the natural bone to reduce the stress shielding phenomenon.

骨科植入物的长期生存率仍然是一个挑战，因为患者越来越年轻，越来越活跃。影响种植体寿命的一个因素是骨吸收，据信是由于应力遮挡。骨是一种活组织，对机械刺激有反应。当骨被移除以被人工植入物替代时，骨内的应力发生重新分布。这种应力遮挡现象的发生是因为金属植入物和周围骨之间的刚度差异很大。因此，骨被应力屏蔽，因此骨被再吸收并且其密度降低，最终导致关节成形术失败。需要新的材料来模拟天然骨以减少应力遮挡现象。