Understanding how the Linker of Nucleoskeleton and Cytoskeleton Complex Mediated Changes in Gene Expression Regulate Satellite Cell Cycle

了解核骨架和细胞骨架复合物的连接体如何介导基因表达的变化调节卫星细胞周期

• 批准号: 386623
• 负责人: McKee-Muir Olivia
• 金额: $ 1.27万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-12-01 至 2018-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=386623&lang=en
• 关键词: Cell Cycle; Emery-Dreifuss Muscular Dystrophy; Gene Transcription; Linc Complex; Mechanotransduction; Muscle Stem Cells; Regeneration; Stem Cell Differentiation

Emery-Dreifuss muscular dystrophy (EDMD) is a disease with symptoms that include skeletal muscle weakness and wasting as well as cardiac problems. Patients with EDMD often have mutations in genes that code for proteins that form the Linker of Nucleoskele

Emery-Dreifuss肌营养不良症（EDMD）是一种症状包括骨骼肌无力和萎缩以及心脏问题的疾病。EDMD患者通常在编码形成核骨架连接子的蛋白质的基因中发生突变