Identification of Lipoma Preferred Partner (LPP) protein interaction networks critical for invadopodia formation and breast cancer metastasis

鉴定对侵袭伪足形成和乳腺癌转移至关重要的脂肪瘤优选伴侣 (LPP) 蛋白相互作用网络

• 批准号: 386645
• 负责人: Voorand Elena M
• 金额: $ 1.27万
• 依托单位: McGill University
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-12-01 至 2018-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=386645&lang=en
• 关键词: Breast Cancer Metastasis; Cell Cytoskeletal Organization; Cell Invasion And Migration; Erbb2-Mediated Breast Cancer; Extracellular Matrix Interactions; Invadopodia; Lipoma Preferred Partner (Lpp); Protein Interactome; Src Phosphorylation Of Lpp; Tumour Mi

Unfortunately, the development of metastatic breast cancer presents a very poor prognosis for many patients. Research into the mechanisms associated with the occurrence of metastasis is therefore important for creating therapies directed at controlling ca

不幸的是，转移性乳腺癌的发展对许多患者来说预后非常差。因此，研究与转移发生相关的机制对于创造针对控制肿瘤的治疗方法是重要的。