Spatially encoded mass spectrometry data for intrasurgical pathology

用于外科病理学的空间编码质谱数据

• 批准号: 516328-2017
• 负责人: Jaffray, David
• 金额: $ 1.82万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Engage Grants Program
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=640152
• 关键词: Spatially; encoded; mass; spectrometry; data

A surgical laser developed by an Ontario-based industrial partner could have additional capabilities to helpincrease its value in the operating room. By leveraging the expertise, track record, previous developments andinfrastructure of the academic partner, a new laser scalpel will be developed that is capable of deliveringspatially resolved pathology results to surgeons. Further development and integration with academic partner'sexisting technologies will result in a platform that can display information that can be used to classify tissue ashealthy or cancerous -- and subtype the tumour -- using a technique called mass spectroscopy. This molecularinformation can be displayed in real time to surgeons, guiding them to the areas of the tumour to be surgicallyremoved. This insight can transform how surgeons approach cancer surgeries, improving the health ofCanadians and increasing the value of the Canadian technology.

安大略省一家工业合作伙伴开发的手术激光器可能具有额外的功能，有助于提高其在手术室中的价值。通过利用学术合作伙伴的专业知识、跟踪记录、以前的发展和基础设施，将开发一种新型激光手术刀，能够为外科医生提供空间解析的病理结果。与学术合作伙伴现有技术的进一步开发和整合将产生一个平台，该平台可以显示可用于分类健康组织或癌变组织的信息，并使用一种称为质谱的技术对肿瘤进行分类。这些分子信息可以实时显示给外科医生，引导他们到达需要手术切除的肿瘤区域。这种见解可以改变外科医生治疗癌症手术的方式，改善加拿大人的健康状况，增加加拿大技术的价值。