Deciphering the blueprint of the healthy and diseased human brain through the generation of patterned cerebral organoids

通过生成图案化的大脑类器官来解读健康和患病人类大脑的蓝图

• 批准号: 378880
• 负责人: Schuurmans Carol J
• 金额: --
• 依托单位: Sunnybrook Research Institute (Toronto, Ontario)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2018
• 资助国家: 加拿大
• 起止时间: 2018-02-01 至 2021-02-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=378880&lang=en
• 关键词: Autism Spectrum Disorder; Cajal-Retzius Neurons; Cerebral Organoid; Crispr Gene Editing; Hippocampus; Morphogens; Motor, Visual, Auditory, Somatosensory; Primary Neocortical Areas; Regional Patterning; Thalamic Organoids/Explants

The cerebral cortex is the region of the brain that allows us to sense the environment by sight, sound, touch, and smell, and to respond to it by movement or communication. The cerebral cortex also allows us to experience complex human emotions such as lo

大脑皮层是大脑的一个区域，它允许我们通过视觉、听觉、触觉和嗅觉来感知环境，并通过运动或交流来对环境做出反应。大脑皮层还允许我们体验复杂的人类情感，如LO