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Lysosomal dysfunction in smooth muscle cells relative to macrophages provides new insights into foam cell lipid accumulation

Lysosomal dysfunction in smooth muscle cells relative to macrophages provides new insights into foam cell lipid accumulation
平滑肌细胞相对于巨噬细胞的溶酶体功能障碍为泡沫细胞脂质积累提供了新的见解
批准号:
383114
负责人:
Dubland Joshua
金额:
$0.07万
依托单位国家:
加拿大
项目类别:
财政年份:
2018
资助国家:
加拿大
项目状态:
已结题
起止时间:
2018-02-01 至 2019-02-01
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中文摘要
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英文摘要
Lysosomes are central to the metabolism of LDL-cholesterol and play an important role in both generation of foam cells in atherosclerosis and the removal of excess lipids from arterial lesions. We have previously found that smooth muscle cells (SMCs) make
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